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Scientific ArticlesNeoadjuvant Taxane Plus Trastuzumab and Pertuzumab With or Without Carboplatin in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: The Randomized Noninferiority Phase III neoCARHP Trial12 May 2026
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Scientific ArticlesUpfront Modified FOLFOXIRI Plus Panitumumab for RAS/BRAF Wild-Type Metastatic Colorectal Cancer: Final Results of the Phase III TRIPLETE Study17 Feb 2026
Scientific ArticlesNeoadjuvant CTLA-4/PD-(L)1 Blockade Versus Surgery +/- Chemotherapy in Deficient Mismatch Repair/Microsatellite Instability-High Resectable Gastroesophageal Adenocarcinoma: Individual Patient Data Pooled Analysis10 Feb 2026
Scientific ArticlesTrastuzumab Deruxtecan plus Pertuzumab for HER2-Positive Metastatic Breast Cancer02 Dec 2025
Scientific ArticlesThe Impact of Concordance Between Liquid and Tissue Biopsy for Actionable Mutations: Insights from the Rome Trial07 Oct 2025
Scientific ArticlesZanidatamab plus chemotherapy as first-line treatment for patients with HER2-positive advanced gastro-oesophageal adenocarcinoma: primary results of a multicentre, single-arm, phase 2 study30 Sep 2025
Scientific ArticlesNivolumab plus ipilimumab versus lenvatinib or sorafenib as first-line treatment for unresectable hepatocellular carcinoma (CheckMate 9DW): an open-label, randomised, phase 3 trial29 Jul 2025
Scientific ArticlesRelacorilant and nab-paclitaxel in patients with platinum-resistant ovarian cancer (ROSELLA): an open-label, randomised, controlled, phase 3 trial22 Jul 2025
Scientific ArticlesOverall Survival with Inavolisib in PIK3CA-Mutated Advanced Breast Cancer15 Jul 2025
Scientific ArticlesAvelumab plus sacituzumab govitecan versus avelumab monotherapy as first-line maintenance treatment in patients with advanced urothelial carcinoma: JAVELIN Bladder Medley interim analysis08 Jul 2025
Scientific ArticlesVepdegestrant, a PROTAC Estrogen Receptor Degrader, in Advanced Breast Cancer17 Jun 2025
Scientific ArticlesOverall Survival Analysis of the Phase III CodeBreaK 300 Study of Sotorasib Plus Panitumumab Versus Investigator’s Choice in Chemorefractory KRAS G12C Colorectal Cancer20 May 2025
Scientific ArticlesPrognostic implications of risk definitions from the monarchE and NATALEE trials13 May 2025
Scientific ArticlesCamrelizumab vs Placebo in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-Negative Breast Cancer: The CamRelief Randomized Clinical Trial06 May 2025
Scientific ArticlesPerioperative Chemotherapy or Preoperative Chemoradiotherapy in Esophageal Cancer25 Mar 2025
Scientific ArticlesNeoadjuvant and Adjuvant Osimertinib in Stage IA to IIIA, EGFR-Mutant NSCLC (NORA)18 Mar 2025
Scientific ArticlesThree-Year Overall Survival With Nivolumab Plus Relatlimab in Advanced Melanoma From RELATIVITY-04705 Mar 2025
Scientific ArticlesNeoadjuvant nivolumab and chemotherapy in early estrogen receptor-positive breast cancer: a randomized phase 3 trial25 Feb 2025
Scientific ArticlesEncorafenib, cetuximab and chemotherapy in BRAF-mutant colorectal cancer: a randomized phase 3 trial18 Feb 2025
Scientific ArticlesThermal ablation versus surgical resection of small-size colorectal liver metastases (COLLISION): an international, randomised, controlled, phase 3 non-inferiority trial11 Feb 2025
Scientific ArticlesTrastuzumab-Pertuzumab Plus Eribulin or Taxane as First-Line Chemotherapy for Human Epidermal Growth Factor 2-Positive Locally Advanced/Metastatic Breast Cancer: The Randomized Noninferiority Phase III EMERALD Trial28 Jan 2025
Scientific ArticlesAxillary Surgery in Breast Cancer – Primary Results of the INSEMA Trial21 Jan 2025
Scientific ArticlesA randomized study of 6 versus 3 years of adjuvant imatinib in patients with localized GIST at high risk of relapse19 Nov 2024
Scientific ArticlesAn open-label study of pemigatinib in cholangiocarcinoma: final results from FIGHT-20210 Sep 2024
Scientific ArticlesCigarette Smoking and E-cigarette Use Induce Shared DNA Methylation Changes Linked to Carcinogenesis03 Sep 2024
Scientific ArticlesAmivantamab plus Lazertinib in Previously Untreated EGFR-Mutated Advanced NSCLC23 Jul 2024
Scientific ArticlesNeoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer09 Jul 2024
Scientific ArticlesThe PARTNER trial of neoadjuvant olaparib with chemotherapy in triple-negative breast cancer04 Jun 2024
Scientific ArticlesFinal Results From the Randomized Phase III ASCENT Clinical Trial in Metastatic Triple-Negative Breast Cancer and Association of Outcomes by Human Epidermal Growth Factor Receptor 2 and Trophoblast Cell Surface Antigen 2 Expression28 May 2024
Scientific ArticlesPembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial21 May 2024
Scientific ArticlesTranslational and therapeutic evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers07 May 2024
Scientific ArticlesEnfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer09 Apr 2024
Scientific ArticlesFinal analysis of phase II results with cemiplimab in metastatic basal cell carcinoma after hedgehog pathway inhibitors02 Apr 2024
Scientific ArticlesFour-year overall survival update from the phase III HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma26 Mar 2024
Scientific ArticlesInternational Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts19 Mar 2024
Scientific ArticlesOsimertinib with or without Chemotherapy in EGFR-Mutated Advanced NSCLC12 Mar 2024
Scientific ArticlesFluorouracil, Leucovorin, and Irinotecan Plus Cetuximab Versus Cetuximab as Maintenance Therapy in First-Line Therapy for RAS and BRAF Wild-Type Metastatic Colorectal Cancer: Phase III ERMES Study05 Mar 2024
Scientific ArticlesPregnancy After Breast Cancer in Young BRCA Carriers: An International Hospital-Based Cohort Study13 Feb 2024
Scientific ArticlesBiomarker Data from the Phase III KATHERINE Study of Adjuvant T-DM1 versus Trastuzumab for Residual Invasive Disease after Neoadjuvant Therapy for HER2-Positive Breast Cancer09 Jan 2024
Scientific ArticlesNALIRIFOX versus nab-paclitaxel and gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma (NAPOLI 3): a randomised, open-label, phase 3 trial19 Dec 2023
Scientific ArticlesThree-Year Overall Survival with Tebentafusp in Metastatic Uveal Melanoma12 Dec 2023
Scientific ArticlesRandomized Trial of Exercise and Nutrition on Chemotherapy Completion and Pathologic Complete Response in Women With Breast Cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis StudyRandomized Trial of Exercise and Nutrition on Chemotherapy Completion and Pathologic Complete Response in Women With Breast Cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis Study05 Dec 2023
Scientific ArticlesA Phase 3, Randomized study of atezolizumab plus bevacizumab and chemotherapy in patients with EGFR or ALK mutated in non-small cell lung cancer (ATTLAS, KCSG-LU19-04)28 Nov 2023
Scientific ArticlesSotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C21 Nov 2023
Scientific ArticlesFruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study17 Oct 2023
Scientific ArticlesAssociation Between Duration of Immunotherapy and Overall Survival in Advanced Non–Small Cell Lung10 Oct 2023
Scientific ArticlesRisk of Further Progression or Death Among Durable Progression-Free Survivors With Melanoma or Non–Small-Cell Lung Cancer in PD-1 Blockade Trials: Implications for Imaging Surveillance03 Oct 2023
Scientific ArticlesPerioperative Nivolumab and Chemotherapy in Stage III Non-Small-Cell Lung Cancer30 Aug 2023
Scientific ArticlesTrastuzumab deruxtecan in patients in the USA and Europe with HER2-positive advanced gastric or gastroesophageal junction cancer with disease progression on or after a trastuzumab-containing regimen (DESTINY-Gastric02): primary and updated analyses from a single-arm, phase 2 study18 Jul 2023
Scientific ArticlesAtezolizumab plus cabozantinib versus cabozantinib monotherapy for patients with renal cell carcinoma after progression with previous immune checkpoint inhibitor treatment (CONTACT-03): a multicentre, randomised, open-label, phase 3 trial04 Jul 2023
Scientific ArticlesTemporary treatment cessation versus continuation of first-line tyrosine kinase inhibitor in patients with advanced clear cell renal cell carcinoma (STAR): an open-label, non-inferiority, randomised, controlled, phase 2/3 trial23 May 2023
Scientific ArticlesTrifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer16 May 2023
Scientific ArticlesPanitumumab vs Bevacizumab Added to Standard First-line Chemotherapy and Overall Survival Among Patients With RAS Wild-type, Left-Sided Metastatic Colorectal Cancer A Randomized Clinical Trial09 May 2023
Scientific ArticlesFifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer04 Apr 2023
Scientific ArticlesAn international, open-label, randomised trial comparing a two-step approach versus the standard three-step approach of the WHO analgesic ladder in patients with cancer28 Mar 2023
Scientific ArticlesLobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer21 Mar 2023
Scientific ArticlesAdjuvant Osimertinib for Resected EGFR-Mutated Stage IB-IIIA Non-Small-Cell Lung Cancer: Updated Results From the Phase III Randomized ADAURA Trial07 Mar 2023
Scientific ArticlesOlaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2, or ATM Alterations Identified by Testing Circulating Tumor DNA14 Feb 2023
Scientific ArticlesOverall Survival With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation: The SOLO1/GOG 3004 Trial31 Jan 2023
Scientific ArticlesAdagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C24 Jan 2023
Scientific ArticlesPembrolizumab Versus Placebo as Second-Line Therapy in Patients From Asia With Advanced Hepatocellular Carcinoma: A Randomized, Double-Blind, Phase III Trial10 Jan 2023
Scientific ArticlesOverall survival with first-line atezolizumab in combination with vemurafenib and cobimetinib in BRAFV600 mutation-positive advanced melanoma (IMspire150): second interim analysis of a multicentre, randomised, phase 3 study13 Dec 2022
Scientific ArticlesUpfront FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of patients with metastatic colorectal cancer (AtezoTRIBE): a multicentre, open label, randomised, controlled, phase 2 trial06 Dec 2022
Scientific ArticlesEffect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death29 Nov 2022
Scientific ArticlesFirst-line avelumab for patients with PD-L1-positive metastatic or locally advanced urothelial cancer who are unfit for cisplatin23 Nov 2022
Scientific ArticlesFive-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non-Small Cell Lung Cancer in CheckMate 22709 Nov 2022
Scientific ArticlesNeoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous-Cell Carcinoma19 Oct 2022
Scientific ArticlesAddition of androgen receptor targeted agents to androgen deprivation therapy and docetaxel in metastatic hormone-sensitive prostate cancer: a systematic review and meta-analysis12 Oct 2022
Scientific ArticlesPembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial05 Oct 2022
Scientific ArticlesAssociation of Upfront Peptide Receptor Radionuclide Therapy With Progression-Free Survival Among Patients With Enteropancreatic Neuroendocrine Tumors29 Sep 2022
Scientific ArticlesCirculating tumor DNA to guide rechallenge with panitumumab in metastatic colorectal cancer: the phase 2 CHRONOS trial21 Sep 2022
Scientific ArticlesLong-Term Outcomes and Genetic Predictors of Response to Metastasis-Directed Therapy Versus Observation in Oligometastatic Prostate Cancer: Analysis of STOMP and ORIOLE Trials14 Sep 2022
Scientific ArticlesPembrolizumab plus Chemotherapy in Advanced Triple-Negative Breast Cancer07 Sep 2022
Scientific ArticlesModification of the Association Between Frequent Aspirin Use and Ovarian Cancer Risk: A Meta-Analysis Using Individual-Level Data From Two Ovarian Cancer Consortia31 Aug 2022
Scientific ArticlesTrastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer13 Jul 2022
Scientific ArticlesNivolumab plus cabozantinib versus sunitinib in first-line treatment for advanced renal cell carcinoma (CheckMate 9ER): long-term follow-up results from an open-label, randomised, phase 3 trial06 Jul 2022
Scientific ArticlesUpfront Modified Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan Plus Panitumumab Versus Fluorouracil, Leucovorin, and Oxaliplatin Plus Panitumumab for Patients With RAS/BRAF Wild-Type Metastatic Colorectal Cancer: The Phase III TRIPLETE Study by GONO29 Jun 2022
Scientific ArticlesAdebrelimab or placebo plus carboplatin and etoposide as first-line treatment for extensive-stage small-cell lung cancer (CAPSTONE-1): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial15 Jun 2022
Scientific ArticlesFinal Analysis of 3 Versus 6 Months of Adjuvant Oxaliplatin and Fluoropyrimidine-Based Therapy in Patients With Stage III Colon Cancer: The Randomized Phase III ACHIEVE Trial25 May 2022
Scientific ArticlesTemozolomide Followed by Combination With Low-Dose Ipilimumab and Nivolumab in Patients With Microsatellite-Stable, O 6-Methylguanine-DNA Methyltransferase-Silenced Metastatic Colorectal Cancer: The MAYA Trial18 May 2022